曾其伟 副研究员，硕士生导师
尊龙凯时
Contact Us（联系方式）：023-68251903
E-mail（邮件）: [email protected]
教育背景
2003-2010 西南大学生物技术中心，农学博士
1999-2003 西南农业大学，作物遗传育种专业，农学学位
工作经历
2017-至今 尊龙凯时 副研究员
2016-2017 美国加州大学San Diego分校 访问学者
2011-2016 家蚕基因组生物学国家重点尊龙凯时 讲师
研究领域
主要以桑树为研究对象，从事桑属分子分类、桑树基因功能研究工具和体系研究。具体主要包括：
1. 桑属分子分类
以桑树核糖体DNA序列、叶绿体基因组、线粒体基因组以及全基因组单拷贝核基因修订多变的桑属形态学分类，解析白桑的起源与驯化。
2. 桑树基因功能研究工具和体系
1.利用发育调控因子研发桑树毛状根芽再生体系
2. 以桑树双生病毒复制子为工具，建立桑树病毒介导基因功能研究体系、基因编辑体系
3. 以垂桑完整基因组为参考，开展桑树种质资源群体遗传、进化分析，探索栽培桑进化、解析桑优势性状分子机理。
学术贡献
解析桑属植物分类，利用核糖体DNA序列、叶绿体基因组等修订复杂多变的桑属形态学分类。建立桑属植物快速繁殖体系，研发桑树病毒介导基因功能研究体系、基因编辑体系以及农杆菌介导遗传转化体系。完成垂桑完整基因组组装和注释。作为课题负责人承担国家青年科学基金项目“单倍体川桑转座激活标签突变库的构建”、新疆自治区科技援疆项目“新疆特殊环境优势资源筛选及技术示范”、西南大学博士启动项目“22倍体新疆药桑遗传再生体系创建”、西南大学基本业务项目“桑树细胞分裂素氧化酶基因的克隆”，作为骨干参与”中国桑树基因组计划”，863项目“桑树功能基因组学研究与应用”、国家重点研发计划项目子课题“桑树重要品质性状形成与调控”以及商务部茧丝绸产业公共服务体系项目等项目。在Nature biotechnology，Nature communications, Horticulture Research，Journal of Integrative Plant Biology，Journal of Genetics and Genomics，Frontiers in Plant Science，Plos One, Plant molecular biology reporter,等杂志发表论文，参编专著《桑树基因组》，兼任Frontiers in Plant Science审稿人。获得授权专利四项。
荣誉奖励
2020 重庆市科学技术奖“自然科学” 一等奖（4/5）
代表性论文
1. Zhen Yang, Yiwei Luo, Xiaoyu Xia, Jinzhi He, Jiajia Zhang, Qiwei Zeng, Dong Li, Bi Ma, Shaoyu Zhang, Changxin Zhai, Miao Chen, Ningjia He. Dehydrogenase MnGutB1 catalyzes 1-deoxynojirimycin biosynthesis in mulberry. Plant Physiology, 2023, 192(2): 1307-1320
2. Qiwei Zeng, Miao, Chen, Shouchang Wang, Xiaoxiang Xu, Tian Li, Zhonghuai Xiang, Ningjia He. Comparative and phylogenetic analyses of the chloroplast genome reveal the taxonomy of the Morus genus. Frontiers in Plant Science. 2022,13, doi: 10.3389/fpls.2022.1047592
3. Yahui Xuan, Bi Ma, Dong Li, Yu Tian, Qiwei Zeng, Ningjia He. Chromosome restructuring and number change during the evolution of Morus notabilis and Morus alba. Horticulture Research, 2022, 9, doi: 10.1093/hr/uhab030
4. Youchao Xin, Bi Ma, Qiwei Zeng, Wenmin He, Meiling Qin, Ningjia He. Dynamic changes in transposable element and gene methylation in mulberry (Morus notabilis) in response to Botrytis cinerea. Horticulture Research, 2021, 8: 154
5. Gao, Yangbin, Dai, Xinhua, Aoi, Yuki, Takebayashi, Yumiko, Yang, Liping, Guo, Xiaorui, Zeng, Qiwei, Yu, Hanchuanzhi, Kasahara, Hiroyuki, Zhao, Yunde. Two homologous INDOLE-3-ACETAMIDE (IAM) HYDROLASE genes are required for the auxin effects of IAM in Arabidopsis. Journal of Genetics and Genomics, 2020, 47(3): 157-165
6. Han Li, Zhen Yang, Qiwei Zeng, Shibo Wang, Yiwei Luo, Yan Huang, Youchao Xin, Ningjia He. Abnormal expression of bHLH3 disrupts a flavonoid homeostasis network, causing differences in pigment composition among mulberry fruits. Horticulture Research, 2020, 7: 83, doi: 10.1038/s41438-020-0302-8
7. Li, Han, Li, Dong, Yang, Zhen, Zeng, Qiwei, Luo, Yiwei, He, Ningjia. Flavones Produced by Mulberry Flavone Synthase Type I Constitute a Defense Line against the Ultraviolet-B Stress. Plants-Basel, 2020, 9(2): 215, doi: 10.3390/plants9020215.
8. Juan Zhao, Wenqin Bai, Qiwei Zeng, Shuiqing Song, Mi Zhang, Xianbi Li, Lei Hou, Yuehua Xiao, Ming Luo, Demou Li, Xiaoying Luo, Yan Pei. Moderately enhancing cytokinin level by down-regulation of GhCKX expression in cotton concurrently increases fiber and seed yield. Molecular Breeding, 2015, 35(2):60, doi: 10.1007/s11032-015-0232-6
9. Xuwei Wang, Ningjia He, Qiwei Zeng, Zhonghuai Xiang. Identification and expression analyses of chitinase genes in mulberry (Morus L) plants. Plant Omics Journal, 2015, 8(2): 183-189
10. Qiwei Zeng, Hongyu Chen, Chao Zhang, Minjing Han, Tian Li, Xiwu Qi, Zhonghuai Xiang, Ningjia He. Definition of Eight Mulberry Species in the Genus Morus by Internal Transcribed Spacer-Based Phylogeny, PLoS ONE, 2015, 10(8): e0135411, doi: 10.1371/journal.pone.0135411
11. Xiwu Qi，Qin Shuai，Hu Chen，Li Fan，Qiwei Zeng，Ningjia He. Cloning and expression analyses of the anthocyanin biosynthetic genes in mulberry plants. Molecular Genetics and Genomics, 2014, 289(5): 783-793, doi: 10.1007/s00438-014-0851-3
12. Bi Ma, Yiwei Luo, Ling Jia, Xiwu Qi, Qiwei Zeng, Zhonghuai Xiang, Ningjia He. Identification and characterization of cytochrome P450 genes in the mulberry, Morus notabilis. Journal of integrative plant biology, 2014, 56(9):887-901
13. Qing Wang, Bi Ma, Xiwu Qi, Qing Guo, Xuwei Wang, Qiwei Zeng and Ningjia He. Identification and characterization of genes involved in the jasmonate biosynthetic and signaling pathways in mulberry (Morus notabilis). Journal of integrative plant biology, 2014, doi: 10.1111/jipb.12166.
14. Congjin Wei, Xueqin Liu, Dingpei Long, Qing Guo, Yuan Fang, Chenkai Bian, Dayan Zhang, Qiwei Zeng, Zhonghuai Xiang, Aichun Zhao. Molecular cloning and expression analysis of mulberry MAPK gene family. Plant Physiology and Biochemistry, 2014, 77: 108-116.
15. Jingzhe Shang, Penghua Song, Bi Ma, Xiwu Qi, Qiwei Zeng, Zhonghuai Xiang, Ningjia He. Identification of the mulberry genes involved in ethylene biosynthesis and signaling pathways and the expression of MaERF-B2-1 and MaERF-B2-2 in the response to flooding stress. Functional & Integrative Genomics, 2014, 14(4):767-777, doi: 10.1007/s10142-014-0403-2
16. Ningjia He, Chi Zhang, Xiwu Qi, Shancen Zhao, Yong Tao, Guojun Yang, Tae-Ho Lee, Xiyin Wang,Qingle Cai, Dong Li,, Mengzhu Lu, Sentai Liao, Guoqing Luo, Rongjun He, Xu Tan, Yunmin Xu, Tian Li, Aichun Zhao, Ling Jia, Qiang Fu, Qiwei Zeng, Chuan Gao etc. Draft genome sequence of the mulberry tree Morus notabilis. Nature Communications, 2013, doi: 10.1038/ncomms3445.
17. Tian Li, Xiwu Qi, Qiwei Zeng, Zhonghuai Xiang and Ningjia He. MorusDB: a resource for mulberry genomics and genome biology. Database (Oxford), 2013, doi: 10.1093/database/bau054.
18. Zeng, Qi-wei, Qin Shan, Song, Shui-qing, Zhang, Mi, Xiao, Yue-hua, Luo, Ming, Hou, Lei, Pei, Yan. Molecular Cloning and Characterization of a Cytokinin Dehydrogenase Gene from Upland Cotton (Gossypium hirsutum L.). Plant Molecular Biology Reporter, 2012, 30(1): 1-9
19. Mi Zhang, Xuelian Zheng, Shuiqing Song, Qiwei Zeng, et al. Spatiotemporal manipulation of auxin biosynthesis in cotton ovule epidermal cells enhances fiber yield and quality. Nature Biotechnology, 2011, 29, 453–458