程廷才 教授，博士生导师
尊龙凯时
Contact Us（联系方式）：
E-mail（邮件）: chengtc@zunlongks.org
教育背景
2004-2008 西南大学蚕学与系统生物学研究所 博士
2002-2004 西南大学蚕学与系统生物学研究所 硕士
1997-2001 西南农业大学蚕桑丝绸学院 本科
工作经历
2012-至今 尊龙凯时 长聘教授
2016-2017 加州大学圣地亚哥分校访问学者
2008-2011 重庆大学农学与生命科学学院副教授
研究领域
主要从事鳞翅目昆虫基因组和比较基因组学、家蚕表观基因组与表观遗传学、家蚕病源微生物与宿主互作等领域的研究，解析了鳞翅目害虫斜纹夜蛾基因组，相关成果发表于Nature子刊Nature Ecology & Evolution，被《重庆新闻联播》、《科学网》等视频媒体和新闻报道。近年来主持和主研包括国家自然科学基金、重庆市自然科学基金、横向合作项目等20余项。担任Insect Biochemistry and Molecular Biology、Molecular Genetics and Genomics、Scientific Reports等杂志审稿人。在Nature Ecology & Evolution、PNAS、PLoS Pathogens、Insect Biochemistry and Molecular Biology、Insect Science等高水平期刊发表论文70余篇。
代表性论文
1） Cao J, Tao C, Qin X, Wu K, Yang H, Liu C, Cheng T. PI3K-Akt-SGF1-Dimm pathway mediates the nutritional regulation of silk protein synthesis in Bombyx mori. Int J Biol Macromol. 2024 Oct;278(Pt 2):134650. doi: 10.1016/j.ijbiomac.2024.134650.
2） Tao C, Li J, Du W, Qin X, Cao J, Liu C, Cheng T. Broad Complex-Z2 directly activates BmMBF2 to inhibit the silk protein synthesis in the silkworm, Bombyx mori. Int J Biol Macromol. 2024 Oct;277(Pt 3):134211. doi: 10.1016/j.ijbiomac.2024.134211.
3） Cao J, Wu K, Wei X, Li J, Liu C, Cheng T. A Simple and Low-Cost CRISPR/Cas9 Knockout System Widely Applicable to Insects. Insects. 2024 May 8;15(5):339. doi: 10.3390/insects15050339.
4） Cao J, Zheng HS, Zhang R, Xu YP, Pan H, Li S, Liu C, Cheng TC. Dimmed gene knockout shortens larval growth and reduces silk yield in the silkworm, Bombyx mori. Insect Mol Biol. 2023 Feb;32(1):26-35. doi: 10.1111/imb.12810.
5） Cheng T, Zhang X, Peng Z, Fan Y, Zhang L, Liu C. Effects of Osiris9a on Silk Properties in Bombyx mori Determined by Transgenic Overexpression. Int J Mol Sci. 2020 Mar 10;21(5):1888. doi: 10.3390/ijms21051888.
6） Feng T, Lin P, Gong J, Cheng D, Yang X, Zhang Q, Cheng T. Gene Expression Pattern and Regulatory Network of α-Toxin Treatment in Bombyx mori. Int J Genomics. 2019 Mar 5;2019:7859121. doi: 10.1155/2019/7859121.
7） Cheng D, Cheng T, Yang X, Zhang Q, Fu J, Feng T, Gong J, Xia Q. The genome-wide transcriptional regulatory landscape of ecdysone in the silkworm. Epigenetics Chromatin. 2018 Aug 27;11(1):48. doi: 10.1186/s13072-018-0216-y.
8） Gong J, Cheng T, Wu Y, Yang X, Feng Q, Mita K. Genome-wide patterns of copy number variations in Spodoptera litura. Genomics. 2019 Dec;111(6):1231-1238. doi: 10.1016/j.ygeno.2018.08.002.
9） Cheng T, Wu J, Wu Y, Chilukuri RV, Huang L, Yamamoto K, Feng L, Li W, Chen Z, Guo H, Liu J, Li S, Wang X, Peng L, Liu D, Guo Y, Fu B, Li Z, Liu C, Chen Y, Tomar A, Hilliou F, Montagné N, Jacquin-Joly E, d'Alençon E, Seth RK, Bhatnagar RK, Jouraku A, Shiotsuki T, Kadono-Okuda K, Promboon A, Smagghe G, Arunkumar KP, Kishino H, Goldsmith MR, Feng Q, Xia Q, Mita K. Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest. Nat Ecol Evol. 2017 Nov;1(11):1747-1756. doi: 10.1038/s41559-017-0314-4.
10） Gan H, Feng T, Wu Y, Liu C, Xia Q, Cheng T. Identification of circular RNA in the Bombyx mori silk gland. Insect Biochem Mol Biol. 2017 Oct;89:97-106. doi: 10.1016/j.ibmb.2017.09.003.
11） Lin P, Cheng T, Ma S, Gao J, Jin S, Jiang L, Xia Q. Bacillus bombysepticus α-Toxin Binding to G Protein-Coupled Receptor Kinase 2 Regulates cAMP/PKA Signaling Pathway to Induce Host Death. PLoS Pathog. 2016 Mar 29;12(3):e1005527. doi: 10.1371/journal.ppat.1005527.
12） Cheng T, Fu B, Wu Y, Long R, Liu C, Xia Q. Transcriptome sequencing and positive selected genes analysis of Bombyx mandarina. PLoS One. 2015 Mar 25;10(3):e0122837. doi: 10.1371/journal.pone.0122837.
13） Cheng TC, Zhang YL, Liu C, Xu PZ, Gao ZH, Xia QY, Xiang ZH. Identification and analysis of Toll-related genes in the domesticated silkworm, Bombyx mori. Dev Comp Immunol. 2008;32(5):464-75. doi: 10.1016/j.dci.2007.03.010.
14） Cheng T, Zhao P, Liu C, Xu P, Gao Z, Xia Q, Xiang Z. Structures, regulatory regions, and inductive expression patterns of antimicrobial peptide genes in the silkworm Bombyx mori. Genomics. 2006 Mar;87(3):356-65. doi: 10.1016/j.ygeno.2005.11.018.
15） Cheng TC, Xia QY, Qian JF, Liu C, Lin Y, Zha XF, Xiang ZH. Mining single nucleotide polymorphisms from EST data of silkworm, Bombyx mori, inbred strain Dazao. Insect Biochem Mol Biol. 2004 Jun;34(6):523-30. doi: 10.1016/j.ibmb.2004.02.004.